The dichloromethane extract of Almeidea coerulea stems yielded the (11-hydroxyrutaecarpine alkaloid reported for
the first time from this species) and the triterpene (28-hydroxy-28, 29-dihydrolupeol). The dictamine, skimianine,
sitosterol and stigmasterol were also isolated from methanol extract. Extracellular forms of Leishmania
amazonensis (promastigotes) was tested with dichloromethane extract and 28-hydroxy-28, 29-dihydrolupeol with
showed anti-leishmanial activity above 0.1 mg/mL and 75μg/mL (inhibited 50% promastigote growth), respectively.
