This article reflects the suffering of groups forced to migrate to urban spaces in the Amazon, severing their ties to the land. Analytical categories from two research groups at Brazilian universities were used, as well as accounts of the psychological distress of the Sateré-Mawé/AM and Hixkaryana/AM Indigenous people presented after their migration to the city. The collection methodology was ethnographic, and the analytical categories were derived from historical-social psychology. The results suggest that the social inequality experienced by Indigenous peoples permeates the suffering experienced in the city, characterized as ethical-political. The concept of health and the category of commons emerged as forms of power for these peoples to live in an urban context